What is Noopept?
Noopept is the brand name for N-phenylacetyl-L-prolyglycine ethyl ester, although it is also known as GVS-111. However, it’s original name was Ноопепт, as it was first developed by a Russian pharmaceutical company.
Noopept is similar to Piracetam, only better because it’s much more potent and effective. It helps with anxiety, attention span, memory, learning, and is even a potential treatment for Alzheimer’s, since research has shown that it can promote nerve growth and cell repair in those experiencing cognitive decline.
Noopept is not one of those nootropics that only provides one or two functions and needs to be stacked to be truly beneficial. It has numerous benefits. Here are the areas in which it’s been shown to make improvements:
- Learning ability
- Problem solving
- Attention span
- Communication within the brain
- Rehabilitation of cerebral trauma through neuroprotective and antioxidant effects.
As well as the effects listed above, Noopept also acts as a stimulant.
How long does it take to feel the effects of Noopept?
When taken orally, Noopept is absorbed and metabolised rapidly. A study using rats showed that Noopept crosses the blood brain barrier easily, coming into effect around 7 minutes after being taken.
How does Noopept work?
Noopept targets the acetylcholine system, working with the NMDA and AMPA receptor sites.
After ingestion and absorption through the GI tract, it crosses the blood-brain barrier quickly, then going on to increase levels of oxygen and glucose metabolism in the brain, as well as inhibiting glutamate breakdown. This results in increased mental energy and enhanced memory, focus and learning ability.
There are some mechanisms of Noopept which scientists aren’t entirely sure of. Firstly, it’s neuroprotective effect, which benefits those who have suffered cognitive trauma, requires more research to determine exactly how it is achieved. Secondly, there is an anti-depressant effect. This has been indicated by animal studies, but there is not yet enough evidence to confirm this.
How to take Noopept – Dosage
Recommended dosage of Noopept is 10-30mg once a day for a maximum of 56 consecutive days. The reason it’s only required in such small doses is that it’s particularly potent. This means that only very little is needed for it to be effective, but it also means that those who use it should take extra care to ensure they don’t exceed the dosage guidelines.
Noopept can be taken via capsule, under the tongue, or in powder form mixed with water. Capsules are the easiest way to ensure that the dosage is accurate and safe.
Noopept can be stacked, ideally with a choline source, such as Alpha GPC. However, it’s not recommended for beginners who are just starting out with nootropics to stack Noopept straight away. Start out with Noopept on its own and then build gradually later on.
Noopept Side Effects
Noopept is generally well-tolerated and the only reported side effects have been mild. This includes irritability after taking it for extensive periods, fatigue, lack of appetite and agitation. Despite being regarded as a type of racetam, a type of drug that often comes hand in hand with headaches, Noopept is not known to cause headaches.
While extensive animal research has been conducted with Noopept, further human research is required. It is therefore recommended to use caution and consult with a doctor before taking Noopept.
Noopept vs. Pirecetam
While Noopept is often compared to Piracetam, it has been proven to be far more effective in multiple aspects. One of those is memory function. While Piracetam aids the early stages of memory process, Noopept ‘positively influences the memory consolidation and retrieval steps as well‘. Noopept also requires a much lower dosage than Piracetam to be effective.
When it comes to cognitive enhancement, Noopept comes out on top once again. Piracetam produces quicker results, but they fade quicker, too. Noopept, on the other hand, stays working for much longer.
A study comparing Noopept to Piracetam reported almost 2 times more side effects with Piracetam, despite using only a 1200mg dose in comparison to a 20mg dose of Noopept.
Absorb Health sell Noopept capsules in bottles of 100 for $19.99. They accept all major credit cards, ship within one business day and have a returns policy, although this is only applicable to orders within the US.
Noopept also available in powder form from NootropicsDepot.com, where it costs $7.99 for a 5g jar and $13.99 for a 10g jar. However, using Noopept as part of a stack is the best way to maximise the benefits. Some of the best Noopept stacks out there are NooShift, NitroVit and Liftmode.
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